Présentation En Anglais Oxycontin

Légende :

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If you know this drug and want to intervene if our words are incomplete, or if you just want to share us your experiences, please do not hesitate either.

WHAT IS OXYCONTIN ?

OxyContin (oxycodone hydrochloride controlled-release) is an opioid analgesic supplied in 10 mg, 15 mg, 20 mg, 30 mg, 40 mg, 60 mg, and 80 mg tablets for oral administration.

The tablet strengths describe the amount of oxycodone per tablet as the hydrochloride salt. The structural formula for oxycodone hydrochloride is as follows:

OxyContin (oxycodone) is a narcotic pain reliever similar to morphine.

OxyContin is used to treat moderate to severe pain that is expected for an extended period of time.

MECHANISM OF ACTION

With morphine, the effect is mediated by µ-opioid receptors

But unlike this one, OxiContin acts on к-opioid receptors.

Research by a Japanese group suggests that the effect of oxycodone is mediated by different receptors in different situations :

– In diabetic mice the к-opioid receptor appears to be involved in the antinociceptive effects of oxycodone

– In non-diabetic mice the µ1-opioid receptor seems to be primarily responsible for these effects.

IMPORTANT INFORMATIONS ABOUT OXYCONTIN

OxyContin may be habit-forming and should be used only by the person it was prescribed for.

Keep the medication in a secure place where others cannot get to it.

Follow the directions on your prescription label.

Do not stop using OxyContin suddenly, or you could have unpleasant withdrawal symptoms.

Ask your doctor how to avoid withdrawal symptoms when you stop using oxycodone.

BEFORE USING OXYCONTIN

Do not use OxyContin if you have ever had an allergic reaction to a narcotic medicine (like methadone, morphine, Oxycontin, Darvocet, Percocet, Vicodin, Lortab, codein, etc...)

You should also not take OxyContin if you are having an asthma attack.

To make sure you can safely take OxyContin, tell your doctor if you have any of these other conditions:

• asthma, sleep apnea

• liver or kidney disease;

• trouble swallowing

• a history of head injury or brain tumor;

• epilepsy

• low blood pressure;

• mental illness, or a history of drug or alcohol addiction.

OXYCONTIN AND PREGNANCY

Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Oxycodone can pass into breast milk and may harm a nursing baby.

You should not breast-feed while

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